Pushing the Boundaries of Shadowrun Stompin' Grounds, Can Shadowrun adapt to settings it wasn't meant for? Options

[Rembrandt]

I was a fairly hardcore DnDer (with some WoD thrown in the mix) when I was introduced to Shadowrun. Luckily, the GM I had could spin a damn good yarn, and so my first experience with the system was excellent.

Unfortunately, all good things must come to an end. After our characters rode off into the sunset, it left a large, gaping hole in our Saturday schedule, one that I wish to fill. I came up with some game ideas that were typical Shadowrun pulp, but then something hit me... what if, instead of taking inner-city street jobs, the Shadowrunners were third-world mercenaries (ala Blood Diamond and Rambo and such)?

I created this whole idea for a game taking place in these poor, deadly, low-tech, uber-violent third-world countries. Obviously, your Street Samurai and Gunbunny would fit right in, as would mages and adepts. There's not much room in there for technomancers, hackers, riggers, faces, and investigators though. Still, the idea of gun-toting orks and crazy combat mages being hired to take out pirates, rebels, and arms smugglers has, I believe, a lot of promise. Rather than being your typical hack in/shoot/slash/get out runs, it would put the players in a much deadlier, much more tactical world that would see them running through the jungle rather than through the city streets.

So here's my question:

Would Shadowrun support a low-tech game, or would taking out the high-level technology (maybe make it low cyberpunk, rather than high cyberpunk, and take away stuff like bioware and cyberware) cause too much imbalance in the rules to be enjoyable?

I rely on your advice, since I'm new to the system.