In general, should contemporary humans be able to pwn old school creepy crawlies?, Technology and firepower vs. principle or tradition, I guess Options

[Wounded Ronin]

In general, do you think that contemporary prepared humans should be able to pwn things which have traditionally been creepy crawly or scary monsters? For example, let's think about an old folkloric vampire, i.e. a walking corpse with an appetite for blood, without necessarily considering super-intelligence such as Stoker's Dracula might have. If we were to imagine a medieval dude with a knife stumbling on an old folkloric vampire in, say, a misty cemetary, we can imagine how it would be tough to deal with said vampire. But what about a a contemporary guy who is prepared with NVGs, a shotgun, and a sidearm? Even if the contemporary person isn't using any specific anti-vampire charms like garlic or whatnot, think about it in terms of physics. The shotgun can remove a head at close range, right? So even if the vampire is supposedly immune to normal weaponry, what can it do against shot going at several thousand feet per second that can make its head into a chunky smear? What can it do without teeth and eyes and a brain, after all? Just think about the raw mangling power of modern weaponry.

The way I see it, if we're talking about a scary monster with human intelligence and/or supernatural age/experience, such as a D&D lich, the question of technology and firepower vs. spookiness should theoretically go out the window since the scary monster can do everything a human can, unless the super intelligent monster has been so isolated it has no idea what a human can do. Like, I can imagine a D&D lich being stuck in a catacomb for 1000 years and looking down on humans so much he expects to find them with platemail and swords and dies just from being totally surprised and unprepared in one critical encounter.

I suppose that another obvious exception would be incorporeal entities, since you by definition really can't shoot those, set them on fire, or whatnot. I suppose which if any contemporary weapons should be able to affect incorporeal monsters is a whole other subject for discussion. But in terms of things like, say, ghouls, werewolves in wolf form, zombies, D&D giant rats, or similar things that are beefier like bone golems or what have you, you'd think that things like plastic explosives, .50 cal rifles, PKM machine guns, white phosphorous and whatnot would be able to pwn those things much more quickly and thoroughly than a crossbow or a stake and mallet. Dare I say trivially easily, with preparation and sufficient ammunition?