I.e. does it affect only mundane perception tests, or would it also affect astral perception?
Beyond the simple question. How do your runners deal with someone getting a material link? (A regular ward just isn't going to cut it once a decent mage gets brought in).
Or would you just say, they got a sample, you're screwed, permanently lose a point of edge and a janitor accidently knocks out the power cord to the refridgeration unit holding your sample.
(One of my players is in this spot, or rather a female he cares for is).