In previous editions, the only time you'd mix tech (cyberware, to be specific) and guard animals would be if you wanted to create psychotic, hair-trigger, killing machines. While those are fun, they were better suited to use as a response weapon, instead of a patrolling deterrent.
There's a new possibility under SR4. With the right obedience training, a set of image-linked doggles (dog goggles) and a specially designed Augmented Reality Environment program, you could have a kennel's worth of roving patrol dogs that don't need handlers to accompany them, can be controlled from a central location like a drone, and will attack specifically designated targets to the exclusion of anything else.
While it's true that dogs have less visual capacity than humans, as long as the visuals of the ARE program are designed with this in mind, it'd be very easy to provide an Augmented Reality Environment that the dog can be trained to respond to.
Want to have patrol dogs and pressure pads in the same facility? You can have certain pressure pads disarm in timed sequence, and have the dog trained to walk just in the areas of floor highlighted on the doggles.
Need to get the dogs to follow randomized patrol paths? Give the dog some AR object that it's trained to follow, like another dog, an AR alpha dog, if you will. This'd also be handy if you needed to get all the dogs in the facility to one place quickly to counter a threat. Pack behavior instinct says when the alpha dog starts running somewhere, you run to follow.
Finally, when doing attack training, train the dogs that they see a person who's been highlighted on their doggles, that's who they attack. Then you set up the system so that if it detects a human silhouette that isn't broadcasting the right RFID, highlight it.
The nice thing is, you could have 20-30 dogs out on patrol, and only have to have one human on payroll in the security office monitoring the image feeds from the doggles. I suppose if you had a smart enough piece of software there instead, you wouldn't even need any human presence.