Gecko gloves don't work so hot in 2070 Seattle... it rains all the time

If you've got a high enough DV with something like spurs or handblades, climbing up the outside of a structure should become pretty easy (since you're not trying to destroy the barrier, just "shoot through" it). Say goodbye to big concrete walls being an effective stopper!
With the combination of 'ware pushing your Body (to let you wear heavier armor), your natural armor (to up your total armor value) and having a decent willpower, possibly something like a platelet factory, and a pain editor or pain resistance, a lot of sams can flat-out ignore the first few hits they take in a gunfight... the damage isn't significant enough to slow them down. But take this even further... hit them with a car, have them use themselves as a shield for another player (wrap him in your arms and turn your back to the incoming fire), have explosives toss them into things, and they just stand back up.
Thrown weapons can become pretty bizarre. I recall a comic I read at one point, where cyborgs used what were essentially depleted Uranium ball bearings as weapons, because they could get them up to a high enough speed that they could go through the armor other 'borgs were wearing. While that might be stretching believability a bit, a high-stat/skill sammie should be able to pull off some pretty amazing knife or shuriken throws... incredibly long ranges, devastating impacts. Not enough for you? Well, that sammie can pick up a motorcycle, right? How about dropping it on someone? How about tearing off a car door, and then throwing it? Punch a building, knock a bunch of bricks loose, and then throw them fifty-plus meters.
Get a sammie with a little bit of rigging ability, give him a sensor network, and he can become the ultimate urban hunter. With a few microdrones like the fly-spy slipped into the rooms around him, crawling through ducts, and things like blimps monitoring the outside of a building, he doesn't need to see his targets to engage them. Guy in the next room over? Put your fist through the sheetrock and drag him back through the wall towards you. People approaching from the front of the building? Get into the kitchen, get the fridge between you and them, stick your smartgun around the corner, and use the smartgun's +2 and the +3 for good AR information to counteract the -6 for blind fire... chew them to pieces through a couple of walls, when they don't even know you're there. Stalk someone with your drones, keep him marked on your AR, and simply leap across rooftops and streets to keep up... your signature is much lower than than a dedicated rigger hanging out in his sedan.
Get some air filters, some eye covers, and a few of the other anti-toxin implants, and all of a sudden you're wading through tear gas, pepper punch, nerve toxins, and puddles of toxic ooze without batting an eye. An urban warrior in the cyberpunk era could move into a superfund site or a plating factory and simply shoot up the environment to generate cover for himself... most people would want hazmat gear to follow him into the fume-ridden, horribly toxic environment he was leaving in his wake.
Trying to flee in your car? If he picks up the front end, your front tires don't have any traction, and you ain't going anywhere without 4-wheel drive. Managed to get going? Sammies (especially when the Kid Stealth legs or the cyberskates come back) might be able to keep up for a while, and they're a hell of a lot more maneuverable in traffic. Watching a sedan drive around traffic, up onto the sidewalk, and generally swerve all over while a sam leaps from cartop to cartop firing at them with his gyrostabilized cybersubmachinegun is probably not entirely unheard of in SR.
Gotta grab something out of liquid nitrogen while under fire, and you don't have any tools handy? When the sammie disables his cyberarm's sensors, forms it into a crook, and reaches right into that liquid N2, it might screw his cyberarm up for good, but if he's elite the run could be worth it.
And you know another thing sams are good for? When you've got to carry a few hundred pounds of gear up ninety flights of stairs,
cyberlegs don't get tired.