I watched the first episode of the Sci-Fi channel's "Who Wants to be a Superhero?" and I think that it's ridiculously awesome. Seeing some of the commercials for it just now got me thinking of an awesome idea for a campaign:
"Who Wants to be a Shadowrunner?"
Ordinary metahumans from all over try out to be the next shadowrunning trid stars! These are, again, people who aren't actually ex-military prime-runner material, but want to be one anyway. Of course, there's nothing stopping a character or two from secretly being awakened (maybe even unknown to them!) or having a couple pieces of cyberware, but they'd be relying more on improvisation.
They compete for an exclusive NERPS advertizing contract, prize money, possibly some trinket left over from Dunkelzahn's Will or something.
Of course, unbeknownst to these average joes, the runs the show sends them on each week are real. Those who fail are voted off... permanently. As the contestants start to figure out that this show is more than pure entertainment (probably after the first gunshot

Now, I'm not really one for GMing, so I'm probably not going to use this. If anyone else likes the idea, feel free to run with it. I just though it would be cool.