Some items would be outside the runners range IF THEY HAD TO BUY IT in the market.
a t-bird or some high grade cyberware, for example, all cost in excess of millions
The problem in some games would be that if the runners got their hands into so much nuyen the entire team would be forced to retire and stop playing. Acting IC is an important concern, why would anyone shoot people in the face for money if money wasn't a problem? Of course, there are "solutions" like the personal vendetta angle, etc, but most of times this would not work for a whole team of runners. Besides, once the monetary incentive to keep shooting people in the face is removed, the game simply isn't the same game anymore...
However, and I am talking from the Gms perspective; there are other ways to work around high availability and high price items, if you consider they would fit your game.
WARNING: LONG STORY AHEAD
A group I am Gming for was doing a pretty nasty run in Yucatán when things got -more- fucked up and they had to bail out. They managed to hijack an Azzie military "Ares Dragon" -"Aztechnology Quetzalcoatl"?
After the jungle was behind they had to hide real low in Nicaragua until they finally fixed transport back to Seattle in a Wuxing container freighter The group decided against selling the chopper because
a. they would not get so much money
[ Spoiler ]
An ares dragon is worth 495k, 30% in the black market, minus at least a 30% because the item was obviously stolen and used -had sniper rifle holes and a very messy cockpit; they calculated they would get about 120k after availabilty was taken into account; that much nuyen, split among six surviving runners -two NPC- would be around 20k, definitely not worth the hassle of selling an Aztech military chopper
b. It would be much too dangerous.
[ Spoiler ]
Selling an Aztech military chopper which went missing in a locked out warzone? in Nicaragua? in Seattle? one of the few reasons the party survived the original run was that nobody was chasing them and nobody knew they were in the jungle. Actually almost nobody who had seen them survived. Selling the chopper would put them in the jungle at complicated times and possibly point the nastiest guns in their direction. Too risky
So the chopper got nicely converted into a "rescue" chopper and got a fake SIN in the name of a fictional NGO; all of this courtesy of some Wuxing favors and 10k nuyen. Now the team's NPC rigger has a chopper on demand for the rest of the group. The runners are still shadowrunners and maybe they can get now into some smuggling runs... oh the possibilities.
I actually hadn't planned they would end the run with a military chopper in their hands, but the moment the run turned out that way I decided to let it happen, adapt and see what happened.
I must say I am glad they didn't sell it, I was of course prepared to let the chips fall their way if they decided to go the nuyen way, but the present outcome is much more enjoyable and the game was quite memorable, particularly for the other two runners who couldn't make it to the hijack zone and were left in the jungle...
Cheers,
Max