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hyzmarca
Okay. If your traditional changling (as opposed to SURGE changeleing) is born human and then goblinizes around puberty in response to the mana level.

This, however, raises an interesting question. If you clone a changeling's organs in a low-mana environment, such as space would they come out as human organs?
Depending on exactly how mana causes goblinization and exactly how organs are cloned, there are potential arguments for both possibilities.

However, even if the answer is no, it should be indisputable that cloned organs created in manavoids from tissues harvested before goblinization will be human organs and will only begin to change when exposed to sufficient mana.

This, of course, allows for physical de-goblinization. Though mental attributes would remain unaltered, a changeling desiring to become human again can simply have a full-body transplant, with his brain cut and and placed into a clone body (possibly one with a cyberskull to compensate for differences in cranial structure).

Of course, there are few advantages to a procedure that simply cancels physical bonuses while keeping mental penalties, particularly since massive cosmetic surgery and dermal-deposit removal can potentially allow a troll with a good con skill to pass for a human basketball player without negating physical bonuses.

Still, for a conflicted goblinoid who wants to be human again, this seems like a the most effective way to go. Of course, he'd never be able to leave the mana void without taking the risk that his new body will goblinize. However, this can be remedied by using a generic type-O human body instead of customized cloned body.
The Type-O solution should also be available to dwarves and elves and humans who need a quick DNA change.
Apathy
The fact that the mental stats of metas have bonuses or penalties compared to those of their human counterparts could lead one to conclude that there are structural and/or hormonal differences that could possibly make a troll brain incompatible with a human body.
Naysayer
Hmmm, the problem I would see is this: From what I understand, the goblinization is triggered by the effect of a high enough mana-level on the crazy-science-proven, n-dimensional shadow genes that potential changelings carry in their genepool. Something like that. And since cloning will also (re)produce these shadow-genes, (which we must assume, since magical, awakened and goblinized people can get cloned replacements that are automatically also goblinized, magical or whatever) your freshly baked clone would probably re-goblinize as soon as he is exposed to enough mana.
And then, as we have learned from Street Magic, living entities generate a mana-field, even in space.
So your changeling would have to be cloned by robots on an otherwise uninhabited space-station, and as soon as he gets back to earth, he'll just follow his genetic imperative and go troll all over again.

At least, that's how I understand it.
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