Welcome to Shadowrun. The game is a blast. Somehow I always come back to this game from every other that I play - Alternity to DnD... It just doesn't matter.
If you are looking for a bit of guidance I would suggest the following. Get some practical experience with character creation by making a folder of NPCs. About 10-15 should do. Just make a Fixer, an Arms Dealer, a few BTL Runners, a Smuggler, Street Doc etc. Fill in the major roles and add a few that might become villains. This will give you an opportunity to feel out what is possible at various BP levels. Also, this sort of practical experience will come in very handy when your players come to you with questions about
their characters during creation.
Another suggestion is to get some dice time however possible. If you have to take two of your NPCs and make them duke it out, do so. Get mitfuls of dice and start to hash out how combat works, how the skills and attributes interact, when you can spend edge etc. The less time you spend looking this stuff up when you have a Live Game, the better.
The Matrix is huge in SR, especially in SR4. Any group worth their salt has some codeslinger. The matrix is, however, extremely complex at first glance. If you are looking for a primer for hackers or technomancers, take a look around the boards for matrix and hacking explanations. A lot of questions have come up and have been answered. I would suggest
The Matrix Explained and
Example Matrix Sites by Knasser as good resources. Lastly,
Serbitar's Guide to Paranoia. An excellent resource for getting your head in the right place for the dystopian techno-future.
If you intend to run Matrix scenarios, dry run them by yourself. Same goes for vehicle engagements and the like. Enough can not be said for knowing the game system when a fresh group come to play.
Finally, as the others have said, SR4 is a highly adaptive game. Theres not really a "right" way to do things - per se. The Right Way is to enjoy yourself as much as possible. Luckily, Shadowrun being so amorphous, you are likely to do just that.
- der menkey
"Certainly there is no hunting like the hunting of man and those who have hunted armed men long enough and liked it, never really care for anything else thereafter."
~ Ernest Hemingway