I was watching "Sweeny Todd" last night and was thinking that it was a great example of a Reaper Toxic physical adept (I know I need to get out more.) I guess the song Epiphany (this takes you to a Youtube video of the song with the lyrics) sums up the entire Toxic philosophy.
However it does seem that from a GM standpoint Toxics are really hard to use properly. They usually come off as cartoony or just stupidly evil. They come across like some type of bad guy from Captain Planet and I think that's why I don't really hear much about people using them.
How do people use Toxic's in your game or what are the reasons that you don't use them?