It's common wisdom that "normal" magic bullets (using Anchoring) are a waste of time and Karma. But what about the occasional "special-purpose" Magic Bullet - i.e., one or two rounds designed to take out very specific targets that otherwise will be damn near impossible to deal with?
I'm thinking of Spirits, Vampires and Shapeshifters in particular - an anchored Pattern with Detect Spirit / Slay Spirit would be a rather useful way to deal with a spirit without having to close with it toe-to-toe or bring in the magician, and silver bullets that have been "blessed" vs. the Infected or Shifters is a reasonably common trope.
Granted, you're looking at something like 10 Karma a piece for anything useful (figure a Force 1 detection spell and a Force 9 Slay spell, just to make *damn* sure whatever it is stays dead), but given that the alternative for mundanes is often being unable to take them down at all, something that can get past Immunity to Normal Weapons and Regeneration seems like a damn useful one-shot device.
What do you think, Sirs?