I was thinking about this question a lot, due to the current topic that floats through the forum and i think i got to a completely different view of it. Basically cyber- and bioware influences your spiritual balance through lowering your essence. For me (and according to the RAW) essence is a vague description of what we would call soul or at least something that keeps your soul grounded to your body. If you put a lot of "unnatural" stuff in your body, the only thing you do, is shrinking your inner flame of life, from a camp-fire to a close-to-the-edge-cigarette-lighter flame. Mana (and especially mana-based-magic) influences exactly this part of your entity. So in my opinion, the less essence you have, the easier is it to blow this little flame out.
Now the argument will come up, that healing magic acts controversly to this opinion, but actually it is quite the other way round. Though your heavy cybering, you lowered your life-power. And the less life power you have left, the more difficult it is to keep it going. Therefore you get penalties to cast healing magic on a cybered character, not because the cyber hinders the magic, but because of your low essence. The spell says only, that you have to subtract your lost essence from the dice-pool, but if you would have no cyber at all, just losing essence e.g. through drugs etc, this modifier should work nevertheless. You see?
This side of view seems (IMHO) more attached to the canon and it even doesn´t afflict the basic rules that technique is the natural enemy of magic (and theoretically the other way round) because you don´t want to influence the technique, but the human around it.^^
I hope i made clear what i wanted to say. Discussing in other languages than your mother-tongue, is quite borderline-esque.^^