Mister Fixer, sir, a question for you, as a long-time veteran of the Shadows.
Two questions.
Suppose that hypothetically, a small business owner with a business in a place like Loveland without any significant ties to the cartels (IE: pays their protection money, but isn't actually being used or overseen or owned by the mobs,) gets on the wrong side of some Runners, for whatever reason. Maybe the Runners took exception to their business practices being especially unethical, maybe their normal business practices, while not all that unethical, wound up inadvertently enabling some other party to do something much more heinous, or maybe the Runners just saw an easy mark.
In short, the Runners decide to squeeze them for some dough; their hacker encrypts the small bisuness's node with some rather strong encryption that would take another hacker to undo. Someone you could hire on the cheap would take days to do it, while someone who'd want a lot of nuyen for the job could do it in a few hours. The Runners in question then offer the small business owner a simple deal: pay unto the Runners the entire expected profit from the most recent thing they did, to the tune of 2,000

to receive the encryption key and thus be able to restore operations as usual. Money to be dropped at a specified time (soon) at a specified place (in Puyallup) by a courier or you're on your own.
In your cost-benefit analysis, would that be a good deal or not? After all, time is money, and taking a small setback on one small piece of criminality is a small price to pay in exchange for being able to resume operations without incident, is it not?
So, would you advise the small business owner to (A) Pay the nuyen and probably get the encryption key needed to unlock all of his matrix systems, with the small risk that the blackmailing party will not pay? (B) Ignore the blackmailing party, who has made it quite clear that the choice is on you to pay or not, and hire a Matrix specialist to bludgeon the encryption open, © ignore the blackmailing party, format and install your systems from scratch, and then spend a few days reinstalling everything and fine-tuning your systems back to the way they were whilst restoring most functionality within an hour or two, or (D) hire a courier to deliver a package to the drop location at the specified time and place, only instead of containing nuyen, it contains a gas bomb with a nerve toxin.
And, on a completely unrelated question,
Suppose you have a Run group which is desperately searching for a little girl whom they were tricked into extracting from legitimate Bad News, but by a third party who has other, completely separate but wholly Bad Intentions for them instead of their legitimate uncle, whom the third party legitimately straight-up murdered and took his identity. Suppose that in the course of this investigation, your leads run mostly dry, but you do manage to track the vehicle the third party used whilst in Seattle, learning that it has been sold as a 'wreck' to a skeevy junkyard operation which has no problem with taking the 'wreck' and driving it to a container ship bound for Hong Kong to be presumably either destroyed or sold by another skeevy outfit, with a listed expected profit of 2,000

all-told. Suppose that the Runners, with their leads dry and frustrated and also possibly desirous of some more cash, decide to punish the skeevy chop-shop by encrypting literally everything in their offices, from the security systems to the payroll to their business ledgers to their login details, using strong encryption that would take even a fantastic hacker about six hours to break through.
Suppose your Runners then decide to offer the skeevy chop-shop an alternative to hiring a hacker and spending six or more hours unencrypting the system by offering to sell them the encryption pass-key; all the owner has to do is have a certified credstick containing 2,000

delivered to a drop point you can easily monitor without it being remotely easy for anyone to pick out who's monitoring it, and you will send him the encryption key. This is a one-time offer that expires when the deadline for delivery passes, and it's up to the chop shop's owner whether he wants to pay the money or spend his time, as his penance for the wrongdoings he has been a part of.
Suppose that instead of delivering money or a hearty frag you, the owner of the chop shop instead delivers a gas bomb containing goddamned Ymir. The pick-up man survives thanks to the simple precaution of taking a gas filter and wearing armor with a chemical seal, but he's in a bad way for a few hours.
And also, suppose that two of the members of this Runner team are Free Spirits of Fire who are capable of dematerializing and returning to this chop-shop junkyard at a moment's notice.
Do you advise your Runners to let this attack on them go, to contact the owner of the bisuness again and demand a much higher sum of money in exchange for not being immediately torched, or to simply have the spirits warp to the business and torch the building and any cars which are whole and ready to be sold into ash and then never contact the owner again.