So, I'm reading Sprawl Wilds and something jumped out at me about how Nanoware is quite possibly the big bugaboo in 5E
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[ Spoiler ]
The mission deals with the Third Mayan Cutter, who's the second Mayan Cutter inhabiting the body of a new person via tainted nanoware. It jumped out at me that this is similar to the AI plague that affected FastJack and several others in Storm Front. Apparently, the nanoware is powerful enough to drop a p-fix, bunraku style (or an AI in Jack's case). A real horror vibe, especially for old runners who were SOTA in fourth edition, but are getting older...