2 passes seems to be the sweet spot (and reduces how frequently people roll for initiative). and it's pretty easy to get to this point in SR4 (edge,gear,drugs,magic) regardless of character archetype.
for goons, I usually have them take 1 IP unless they are aware that the opposition is significantly faster (not every guard in a normal facility is going to take a hit everytime something moves across a remote camera) and then edge up for a second in round 2, or retreat and attempt to regroup/drug up for later combat.
elite security forces (zero-zone and R&D and special ops etc) are a different story of course.