Kicked off an SR4 campaign today, down at the flgs (EndGame in Oakland). We used the book pregens with the exception of my friend [url=http://www.godzillagamingpodcast.libsyn.com/]Mike]/url], and it was everyone's first time with the 4th edition rules. Of six players, three were familar with the 4th ed setting (and older), two only older editions, and one newb. Five of the group are experienced roleplayers.
I used sheets from the Shadowrun fanresources page, including player cheat sheets. I also have the GM screen. I ran the SR Missions episode of "An Once of Prevention". The PC's were a street samurai (custom build by Mike), occult investigator, face, combat mage, troll enforcer.
Everybody enjoyed the session muchly, and wants to play on an every two- to three-week schedule.
Combined with yesterday's Classic Battletech launch party at EndGame, it was a weekend of old school gaming goodness.