I think they actually made that game. I could have sworn I've seen a box cover for Mars Anime-Trail a couple of years ago.
Nope. There is a Oregon Trail II, a Yukon Trail, and an Amazon Trail, but none of these have a cell-shaded spiky-haired teen with an absurdly powerful Winchester who makes corny speeches about the power of friendship.
Unfortunately, Amazon Trail suffers from a lack of candiru.