QUOTE (Dumori @ Apr 16 2010, 01:15 AM)

With the Ks and novacoke they seam to be combat drugs with some form of opiate in them with all that pain resistance.
Well, novacoke is openly refered to as an improved version of cocaine.
Cocaine is a local anesthetic.
It immediately numbs the mucous membranes upon contact, which is why you can see police officers in TV shows testing white powder by dipping it on their tongue (something one shouldn't do in real life, there's enough other white powders where that would already be a lethal dose).
In fact, many local anesthetics used in contemporary medicine are cocaine derivatives which only retain it's anesthetic properties without providing a high.
But effects wise, cocaine's always classified as a simulant.
It also does not work on any opioid receptors, but as an antagonist for serotonin, dopamin and norepinephrin receptors, which is a typical mode of action for stimulants.
One should also keep in mind that many stimulants decrease susceptibility to pain- it's a side effect of being pushed into an adrenaline rush, which makes it different from directly tinkering with the brain's processing of pain, like analgesics do, but may have similar effects, especially in a combat situation.
Can't say anything about K10 or Kamikaze, as both seem not to be based on a real-world substance.
The problem here lies in the classes of stimulants, narcotics, hallucinogens.
Normally, analgesic (pain reliever) would be a class of it's own, as well as local anesthetic or dissociative anesthetic (like ketamine or PCP, for example).
Whereas classic "downer" properties would fall under headers such as tranquilizer, depressant, intoxicant etc.
I'd assume that the latter, in combination with the addictive potential of opiates, would be the reason for the threshold number, not the pain relief or anesthetic factor.
QUOTE
Oxygenated Fluorocarbons (stimulant) really pushing term wise same with a lot of others in the other group I thend to think they shoudl all be threshold 1 or 0. 0 for thing likes zero and slab ect
Oxygenated Fluorocarbons do increase endurance and Agility, that's pretty much classic stimulant territory, which is why i labeled them as such.
I wouldn't rate them as highly addictive, though.
So i'd agree with lower thresholds for them, same for the other examples (though polydrug abuse of Zero and another drug would likely increase the addictive potential of the drug it's combined with).
In any case, one should view the thresholds for the different classes as guidelines (they are presented as such in the BBB anyway).
I'd assume that Hurlg is less addictive than Bliss, even though i'd label both as narcotics.
Slab's a bit problematic here, it's presented mostly as a better version of Narcoject.
It's presentation as a date-rape drug sounds as if it was based on GHB, which does have some addictive potential if used recreationally, but i doubt that this would come up in game.
I agree that it wouldn't make sense to call for an Addiction test if a PC is knocked out with Slab rounds, of course.