My group was once on a Shadowrun to kidnap old people from an old-folk's home (for use in cyborgs, but nobody did the hacking to figure that out...). Not only did they end up kidnapping like 20 people over the age of 75, they also killed like five orderlies/security guards, Powerballed the loading dock door (and some of the dock), kidnapped the holistic shaman on-premises, and dragged a few bodies with them. There were 11 drones used (which is how the first security guy died [the rigger had all 11 drones on one subscription and told that subscription to shoot the guard once with SnS - 11 shots hit the guard for 99S(e) that he heroically reduced to 77S with only 3 Bod and 6 armor that was reduced to 3]), nobody hacked the security cameras or edited/deleted the feeds, and nobody wore masks or helmets.

The way I didn't TPK the group is I created a rival Johnson from the corp that owned the old-folk's home who got their info first and started redirecting info so he could capture them himself. He sent an elite sqaud after the team (I used Tir Ghosts that I reposted here with Capsule Rounds and Slab) while they were doing downtime in their "saferoom" while monitoring the scope of the 'run they had just done. When they came to they were all strapped and constrained in BC for the Awakened facing the J who started on a spiel about how they cost his company a lot of money. As he was monologuing some medical staff took blood samples from the whole team. He went on to say something about liking their more unorthodox heavy hand and how he may have some use for them later. Then they were knocked out and held for a few weeks.

Half of the blood samples were used to force-grow full clones of the team that were placed in a car, had a chase on live-feed Matrix sites, and was attacked and detonated, after "weeks of expert detective work" - the company had the bodies of those responsible they were looking for. The other half was kept as a ritual sample so the J could Ritual cast Dream to contact them at any time to do any thing for free, as many times as he wanted. Since they were now dead, they lost all their contacts from their old life and had to get new SINs and all that, but the group "survived."