So I decided to go with the Vampire controlling some gangers. The main reason I was leaning toward Ghouls was that all the runs so far have been against corp security or some such, and I feel like there is another side that we are missing. Also I liked the idea of further plotlines that were suggested by Sendaz about the Johnson being a front for Tamanous. I may have something with Ghouls in a future mission, and ensure that the Vampire escapes so he can re-occur. Does anyone know of a published or at least posted mission write-up that I can compare what I design against so I know if I am on the right track?
I'm a big fan of false or incomplete information. Maybe the 'runners got intel that there is a vampire with a ghoul entourage, but it turns out just to be gangers on Renfield - they share a lot of the same characteristics, and Renfield will pop you as HMHVV-positive on tests.
I'm sorry buddy, but either you and I read the rules very differently or have significantly different levels of dice pools in our games, 'cause in my book, having a character contract HMHVVIII is basically a "Game Over" sentence for that character. And burning Edge a time or two isn't enough to get through it alive.
Entirely possible that their "normal" is different from yours - I know my "normal" is far and away from others'. Also, ghouls are actually quite amazing, actually. I'd love to play one, especially one that turns during gameplay and has to cope with the stresses of his new condition.
..or everyone plays Shape shifter, they are immune to hmhvv.. 

Rigging is also completely acceptable. It only takes money to get good at Rigging, using the Remote Control rules. Invest a bit in a decent drone and you can go into confined locations against ghouls any time without fear of catching the disease. Just remember to bleach the crap out of the drone before you touch it again...
a critical success is the minimum required hits plus 4 more beyond that. burning edge therefore gives you 12 hits on your resistance test, reducing the disease's power to 0. you still have the disease until enough tests have been made, but as those rolls will be against power 0, that's a relatively minor consideration. whatever you do, don't critically glitch them
(also, don't touch anyone else and burn everything you touched while diseased, because you still have the disease for those 10 days and officially it's spread by contact).

Burning Edge to get a Critical Success is only allowed if the dicepool is high enough where that would be a possibility...
There'd be no point in rolling tests if the test were made against a TN of 0.
Glitching/Critical Glitching. Since there's a possibility of failure, roll them dice.