QUOTE (toturi @ Jan 28 2012, 02:29 PM)
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The way drugs work in SR4 is 'first we give this bonus, then we give this ill effect'. I do not assume that SR4 biochemistry has any more than surface resemblance with real life biochemistry.
QUOTE (Tymeaus Jalynsfein @ Jan 28 2012, 06:26 PM)
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So, Yes, By RAW, Drugs are something you can choose. And secondly, Toturi does have it right. There are Beneficial Effects, and Ill Effects, and they are definitely seperated in the descriptions of the applicable Drug. And I have to agree. Drugs, and their abuse (even the designer ones that have no obvious drawbacks, which is how I would likely utilize the Natural Immunity Quality, as a form of planned avoidance) are a staple of Cyberpunk.
As with most rules, things are abstracted for sake of playability (though at times it seems the results are the opposite of that...)
In most cases, the damage you take from a drug, or the temporarily reduced stats, only come into effect after the drug wears off. If the drug isn't working anymore, how can an immunity to it have any effect?
Even assuming that you still get all the beneficial effects with immunity, the only ill effects that are actually produced by the drug would be any listed 'effects' that can be deemed negative. Take 'Red Mescaline' as an example:
Duration: (18-Body) hours
Effect: +1 Charisma, -1 Reaction, +2 Perception, +1 Willpower, Disorientation
Description: At the end of the duration, Charisma and Willpower are reduced to 1 for an equivalent duration.
The Charisma and Willpower 1 isn't an effect of the drug, it happens after the duration runs out. The Disorientation and -1 Reaction, however, are effects of the drug, and can be deemed 'ill' effects.
I'd say the most liberal interpretation of the RAW would be that you don't suffer Disorientation and -1 Reaction while the drug works, but you still get the Charisma + Willpower reduced to 1 after it wears off. Possibly, addiction could be deemed an ill effect, and if you have immunity you can't get addicted...
Personally, I'd rule that immunity removes all effects, though.